Gliptin New Anti Diabetes Drug Cuts Treatment Cost by 80%

There's a new diabetes drug in the market which apparently cuts cost by 80%. We kid you not. This comes as good news for millions of diabetics tackling the debilitating disease.

By lowering the cost of therapy for patients by 80%, the new drug in the 'gliptin' family has disrupted the anti-diabetes market. With 15 companies offering offering the drugs, cost for a day's treatment is down from Rs 45 to an average daily price of Rs 9. This miracle drug could make life easier for the people tackling with the disease which gradually attacks and weakens all body organs.

The cost of gliptin treatment amounted to Rs 16,200 per year (at Rs 1,350 per month). With the entry of the new molecule and subsequently aggressive pricing by domestic companies over the past six months, the cost of therapy has dropped to approximately Rs 3,285 a year (at Rs 270 a month), translating into national savings of roughly Rs 1,300 crore for patients. The new entrant teneligliptin is also the fastest selling in the Rs 1,430 crore gliptin family which occupies 20% of the total anti-diabetic market.

Diabetics in the country have something to cheer about. A new drug in the 'gliptin' family has disrupted the anti-diabetes market by lowering the cost of therapy for patients by 80%, making it easier for millions of diabetics to tackle the debilitating disease which gradually attacks and weakens all body organs.

With the launch of teneligliptin molecule, the popular gliptin category has witnessed a price erosion of over 80% in the last six months, bringing down the cost from 45 for a day's treatment to an average of 9, with over 15 companies now offering it.

Most gliptins are priced around 45 for a day's therapy, taking the cost of treatment for patients to nearly 16,500 a year ( 1,350 a month).

The entry of the new molecule and subsequent aggressive pricing has led to the cost of therapy coming down to approximately 3,285 a year (or 270 a month), translating into savings of roughly 1,300 crore for patients.

The new entrant teneligliptin is also the fastest selling in the 1,430 crore gliptin family, which occupies 20% of the anti-diabetic market.

Teneligliptin, a third-generation new oral anti-diabetic drug manufactured by Mumbai-based Glenmark, received regulatory approval and was priced aggressively at nearly 20 for a day's therapy when it was first launched in June last year.

The launch of Zita Plus and Ziten (teneligliptin brands) by Glenmark paved the way for the entry of a host of other players to launch the molecule in the oral diabetic market, which is valued around 6,000 crore.

As per AIOCD data (December 2015), there are 16 teneligliptin brands in the market, with total sale of 36 crore.

The economic burden of diabetes is high in India as most patients pay out-of-pocket, and due to lack of medical reimbursement.

Worse, the cost of treatment also includes consultation, investigations, drugs, monitoring, complications, while the complications related to the disease may increase it substantially.

Dr Anoop Misra, chairman Fortis-C-DOC Hospital for Diabetes says, "Low cost medications are surely needed in India, however, all of us look at safety data before prescribing any medication. For teneligliptin, safety data is not long term, and confined to patients from far eastern countries, hence confidence to prescribe this medication viz-a-viz other gliptins is lower."

With the entry of the new molecule, the cost of therapy has dropped to approximatelyRs 3,285 a year (at Rs 270 a month), translating into national savings of roughly Rs 1,300 crore for patients.

EU prepares for future summit

EU prepares a key to the future summit of the euro and to calm markets

Budgetary discipline should be fixed and established mechanisms for joint debt issuance.

The European Council President, Herman Van Rompuy, designed to make the bailout fund with more capabilities and financial resources.

José Luis Rodriguez Zapatero attends his last European Council.

The leaders of the European Union on Wednesday preparing a decisive summit for the future of the euro , which is expected to agree a set of short-term measures to calm the tension in the markets and other long to seal the budgetary discipline and pave the way emissions of common debt.

Twenty-seven are still studying the document sent to them on Tuesday the European Council President, Herman Van Rompuy , with a long list of ideas , including providing the permanent bailout fund (MEDE) with new capabilities and more financial resources.

David Cameron will not accept changes to the treaties without safeguarding the City 's community leader also suggested that the European Stability Mechanism (MEDE), which entered into force will be brought forward to 2012, can participate directly in the recapitalization of banks and also has the characteristics of a lending institution.

The latter would allow unlimited access to the European Central Bank (ECB) and act as a true firewall on the debt crisis , a demand raised by France but had always been rejected by Germany.

Another short-term measures proposed by Van Rompuy is to increase IMF resources through bilateral loans that can help troubled euro countries.

In other respects, Van Rompuy proposed to the Twenty shield the fiscal discipline of the euro countries through various forms of exchange agreements (some of them immediate and easy approval and other long-term and long ratification).

The aim is that the commitment of the countries of the euro fiscal discipline open the door "long term" to the creation of a "joint debt" (Eurobonds, called otherwise).

However, this step only come after a stepwise procedure and on the basis of strict criteria for budgetary discipline and economic competitiveness, according to various sources have been explained and diplomatic community.

Heads of State and Government of the Twenty initiate discussions with an informal working dinner on Thursday, beginning at 18.30 GMT.

The summit will formally begin on Friday morning and will run throughout the day.

Approaching postures

Despite the importance of the meeting, EU sources expect moved that the meeting ends without major delays due to previous contacts have enabled Van Rompuy bring positions in many of the points.

The British Prime Minister David Cameron , arrived in Brussels after having warned that not accept changes to the treaties without safeguards to protect the interests of his country, especially the City , the City of London and an economic engine in the UK.

This will be the last European Council President in office of the Spanish Government, José Luis Rodríguez Zapatero , who leaves office in two weeks after nearly eight years as Executive and a number of community summits to his credit.

Dow Jones lost 4.31%

Wall Street falls 4.31% on a day of widespread turmoil

European indexes all closed with large declines.

This coming will be published official employment data in the U.S..

It's the biggest drop in a single day since December 2008.

The poor performance cause a bad start on the Tokyo Stock Exchange and provide a new day full of turmoil in European markets.

Wall Street on Thursday deepened their losses and the Dow Jones Industrial Average, the main indicator, closed with a sharp drop of 4.31% on a day of widespread turmoil in world markets to doubts about the economic recovery. The index, which comprises the 30 largest U.S. public companies, dismissed the fourth day of the week an impressive 512.76 points to end at 11,383.68 units, which is its biggest drop in a single day since December 2008. Even more pronounced were decreases in the other two major indexes of New York park , as the S & P 500 fell by 4.78% (-60.27 points) to 1200.07 and the Nasdaq composite index fell 5.08% (-136.68 points) to finish at 2556.39. In the final of the day investors turned more in sales that had prevailed throughout the day, responding in part to fears that the crisis debt in the euro zone economies are spreading to more weight as Italy or Spain.