Tuesday, September 20, 2016

Updated Guidelines on PEP

The Centers for Disease Control and Prevention (CDC) has issued new evidence-based guidelines, "Updated Guidelines for Antiretroviral Postexposure Prophylaxis after Sexual, Injection-Drug Use, or Other Nonoccupational Exposure to HIV — United States, 2016" that provide updated recommendations for providers regarding non-occupational post-exposure prophylaxis (nPEP) for exposure to HIV outside the healthcare setting. 

The new guidelines expand on the 2005 U.S. Department of Health and Human Services recommendations and are intended to help reduce the development of new HIV infections via effective nPEP administration to patients following a single exposure to blood, genital secretions, or other potentially infectious bodily fluids that may carry HIV. The 2016 updated guidelines include new scientific data from human and animal studies as well as information on pediatric dosing. In addition, it includes consideration of new antiretroviral drugs that were approved since the 2005 guidelines. 

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